Multifunctional microbubbles and nanobubbles for photoacoustic and ultrasound imaging.

  title={Multifunctional microbubbles and nanobubbles for photoacoustic and ultrasound imaging.},
  author={Chul-hong Kim and Ruogu Qin and Jeff S. Xu and Lihong V. Wang and Ronald X Xu},
  journal={Journal of biomedical optics},
  volume={15 1},
We develop a novel dual-modal contrast agent-encapsulated-ink poly(lactic-co-glycolic acid) (PLGA) microbubbles and nanobubbles-for photoacoustic and ultrasound imaging. Soft gelatin phantoms with embedded tumor simulators of encapsulated-ink PLGA microbubbles and nanobubbles in various concentrations are clearly shown in both photoacoustic and ultrasound images. In addition, using photoacoustic imaging, we successfully image the samples positioned below 1.8-cm-thick chicken breast tissues… CONTINUE READING

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