Multifunctional micelle delivery system for overcoming multidrug resistance of doxorubicin.

@article{Qin2018MultifunctionalMD,
  title={Multifunctional micelle delivery system for overcoming multidrug resistance of doxorubicin.},
  author={Li Qin and Lei Wu and Shanshan Jiang and Dandan Yang and Huiyang He and Fang Zhang and P Zhang},
  journal={Journal of drug targeting},
  year={2018},
  volume={26 4},
  pages={289-295}
}
Doxorubicin (DOX), as an anthracycline, plays an important role in chemotherapy. But multidrug resistance (MDR) tremendously retards the anticancer effect of DOX and results in the failure of chemotherapy. Multifunctional micelles emerge as a valid strategy to load DOX by physical encapsulation or chemical binding to be delivered to cancer cells against MDR… CONTINUE READING