Multifunctional coatings to simultaneously promote osseointegration and prevent infection of orthopaedic implants.

@article{Raphel2016MultifunctionalCT,
  title={Multifunctional coatings to simultaneously promote osseointegration and prevent infection of orthopaedic implants.},
  author={Jordan Raphel and Mark Holodniy and Stuart B Goodman and Sarah C Heilshorn},
  journal={Biomaterials},
  year={2016},
  volume={84},
  pages={301-314}
}
The two leading causes of failure for joint arthroplasty prostheses are aseptic loosening and periprosthetic joint infection. With the number of primary and revision joint replacement surgeries on the rise, strategies to mitigate these failure modes have become increasingly important. Much of the recent work in this field has focused on the design of coatings either to prevent infection while ignoring bone mineralization or vice versa, to promote osseointegration while ignoring microbial… CONTINUE READING
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