Multifunctional Encoded Particles for High-Throughput Biomolecule Analysis

@article{Pregibon2007MultifunctionalEP,
  title={Multifunctional Encoded Particles for High-Throughput Biomolecule Analysis},
  author={Daniel C Pregibon and Mehmet Toner and Patrick S. Doyle},
  journal={Science},
  year={2007},
  volume={315},
  pages={1393 - 1396}
}
High-throughput screening for genetic analysis, combinatorial chemistry, and clinical diagnostics benefits from multiplexing, which allows for the simultaneous assay of several analytes but necessitates an encoding scheme for molecular identification. Current approaches for multiplexed analysis involve complicated or expensive processes for encoding, functionalizing, or decoding active substrates (particles or surfaces) and often yield a very limited number of analyte-specific codes. We present… 
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641 Citations

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