Multifunctional Activities of Green Tea Catechins in Neuroprotection

@article{Mandel2005MultifunctionalAO,
  title={Multifunctional Activities of Green Tea Catechins in Neuroprotection},
  author={S. Mandel and Y. Avramovich-Tirosh and L. Reznichenko and H. Zheng and O. Weinreb and T. Amit and M. Youdim},
  journal={Neurosignals},
  year={2005},
  volume={14},
  pages={46 - 60}
}
Many lines of evidence suggest that oxidative stress resulting in reactive oxygen species (ROS) generation and inflammation play a pivotal role in the age-associated cognitive decline and neuronal loss in neurodegenerative diseases including Alzheimer’s (AD), Parkinson’s (PD) and Huntington’s diseases. One cardinal chemical pathology observed in these disorders is the accumulation of iron at sites where the neurons die. The buildup of an iron gradient in conjunction with ROS (superoxide… Expand
Molecular mechanisms of the neuroprotective/neurorescue action of multi-target green tea polyphenols.
Chelators in the Treatment of Iron Accumulation in Parkinson's Disease
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