Multifork chromosome replication in slow-growing bacteria

@inproceedings{Trojanowski2017MultiforkCR,
  title={Multifork chromosome replication in slow-growing bacteria},
  author={Damian Trojanowski and Joanna Hoł{\'o}wka and Katarzyna Ginda and Dagmara Jakimowicz and Jolanta Zakrzewska-Czerwińska},
  booktitle={Scientific reports},
  year={2017}
}
The growth rates of bacteria must be coordinated with major cell cycle events, including chromosome replication. When the doubling time (Td) is shorter than the duration of chromosome replication (C period), a new round of replication begins before the previous round terminates. Thus, newborn cells inherit partially duplicated chromosomes. This phenomenon, which is termed multifork replication, occurs among fast-growing bacteria such as Escherichia coli and Bacillus subtilis. In contrast, it… CONTINUE READING
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