Multifarious Functions of the Fragile X Mental Retardation Protein.

Abstract

Fragile X syndrome (FXS), a heritable intellectual and autism spectrum disorder (ASD), results from the loss of Fragile X mental retardation protein (FMRP). This neurodevelopmental disease state exhibits neural circuit hyperconnectivity and hyperexcitability. Canonically, FMRP functions as an mRNA-binding translation suppressor, but recent findings have… (More)
DOI: 10.1016/j.tig.2017.07.008

3 Figures and Tables

Topics

  • Presentations referencing similar topics