Multifactorial central nervous system recurrence susceptibility in patients with HER2-positive breast cancer: epidemiological and clinical data from a population-based cancer registry study.

Abstract

BACKGROUND A series of retrospective studies have reported that patients with human epidermal growth factor receptor 2(HER2)-positive breast cancer are at a greater risk of central nervous system (CNS) metastases. Trastuzumab, which does not cross the blood-brain barrier, has been associated with this increased risk. METHODS The authors evaluated… (More)
DOI: 10.1002/cncr.25771

Cite this paper

@article{Musolino2011MultifactorialCN, title={Multifactorial central nervous system recurrence susceptibility in patients with HER2-positive breast cancer: epidemiological and clinical data from a population-based cancer registry study.}, author={Antonino Musolino and Laura Ciccolallo and M Victoria Panebianco and Elisa Fontana and Daniele Zanoni and Cecilia Bozzetti and Maria Michiara and Enrico Maria Silini and Andrea Ardizzoni}, journal={Cancer}, year={2011}, volume={117 9}, pages={1837-46} }