Multifaceted role of EZH2 in breast and prostate tumorigenesis: epigenetics and beyond.

@article{Deb2013MultifacetedRO,
  title={Multifaceted role of EZH2 in breast and prostate tumorigenesis: epigenetics and beyond.},
  author={Gauri Deb and Vijay Singh Thakur and Sanjay Gupta},
  journal={Epigenetics},
  year={2013},
  volume={8 5},
  pages={464-76}
}
Overexpression of EZH2 and other PRC2 subunits, such as SUZ12, is associated with tumor progression and poor prognosis in several human malignancies. Nevertheless, the underlying mechanisms driving aberrant EZH2 expression are poorly understood. This review provides molecular insights into the essential role of EZH2 in breast and prostate tumorigenesis. We… CONTINUE READING

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