Multidrug-resistant breast cancer: current perspectives

  title={Multidrug-resistant breast cancer: current perspectives},
  author={Heather L. Martin and Laura A Smith and Darren Charles Tomlinson},
  booktitle={Breast cancer},
Breast cancer is the most common cancer in women worldwide, and resistance to the current therapeutics, often concurrently, is an increasing clinical challenge. By understanding the molecular mechanisms behind multidrug-resistant breast cancer, new treatments may be developed. Here we review the recent advances in this understanding, emphasizing the common mechanisms underlying resistance to both targeted therapies, notably tamoxifen and trastuzumab, and traditional chemotherapies. We focus… CONTINUE READING
31 Citations
127 References
Similar Papers


Publications citing this paper.
Showing 1-10 of 31 extracted citations


Publications referenced by this paper.
Showing 1-10 of 127 references

Similar Papers

Loading similar papers…