Multidrug Resistance Is Common in Escherichia coli Associated with Ileal Crohn's Disease

  title={Multidrug Resistance Is Common in Escherichia coli Associated with Ileal Crohn's Disease},
  author={Belgin Dogan and Ellen J Scherl and Brian P. Bosworth and Rhonda K. Yantiss and Craig Altier and Patrick L. McDonough and Zhi-Dong Jiang and Herbert Dupont and Philippe Garneau and Jos{\'e}e Harel and Mark Rishniw and Kenneth W. Simpson},
  journal={Inflammatory Bowel Diseases},
Background:Escherichia coli is increasingly implicated in the pathogenesis of ileal Crohn's disease (ICD), offering a potential therapeutic target for disease management. Empirical antimicrobial targeting of ileal E. coli has advantages of economy and speed of implementation, but relies on uniform susceptibility of E. coli to routinely selected antimicrobials to avoid apparent treatment failure. Therefore, we examined the susceptibility of ileal E. coli to such antimicrobials. Methods:E. coli… 

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