Multidisciplinary approach and long-term follow-up in a series of 640 consecutive patients with sarcoidosis

@article{Ma2017MultidisciplinaryAA,
  title={Multidisciplinary approach and long-term follow-up in a series of 640 consecutive patients with sarcoidosis},
  author={Juan Ma{\~n}{\'a} and Manuel Rubio-Rivas and Nadia Villalba and Joaquim Marcoval and A Iriarte and Mar{\'i}a Molina-Molina and Roger Llatj{\'o}s and O S Garcia and Sergio Mart{\'i}nez-Y{\'e}lamos and Vanessa Vicens-Zygmunt and C. Torreblanca Gamez and Ramon M. Pujol and Xavier Corbella},
  journal={Medicine},
  year={2017},
  volume={96}
}
Abstract Cohort studies of large series of patients with sarcoidosis over a long period of time are scarce. The aim of this study is to report a 40-year clinical experience of a large series of patients at Bellvitge University Hospital, a tertiary university hospital in Barcelona, Spain. Diagnosis of sarcoidosis required histological confirmation except in certain specific situations. All patients underwent a prospective study protocol. Clinical assessment and follow-up of patients were… Expand
Elderly sarcoidosis: A comparative study from a 42-year single-centre experience.
TLDR
Aged pulmonary sarcoidosis patients presented with more severe disease at presentation and worse outcomes compared to younger patients, and isolated extrapul pulmonary involvement at diagnosis and certain particular extrapulmonary organ involvement were more frequent in elderly patients. Expand
Child–Adult Transition in Sarcoidosis: A Series of 52 Patients
TLDR
Pediatric-onset sarcoidosis needed a long-term treatment in almost half of the patients, and around one fifth of pediatric-onsets patients had severe sarCOidosis consequences in adulthood. Expand
Epidemiological characterization of patients with sarcoidosis in a high complexity hospital in southwestern Colombia
TLDR
Sarcoidosis was more frequent in women and mestizos, and it presented earlier in men, and Elevated ACE was not associated with extrapulmonary involvement. Expand
Systemic phenotype of sarcoidosis associated with radiological stages. Analysis of 1230 patients.
TLDR
The key determinant associated with a differentiated systemic phenotype of sarcoidosis at diagnosis was interstitial pulmonary involvement rather than the individual Scadding radiological stage. Expand
Epidemiology of sarcoidosis in northern Spain, 1999-2019: A population-based study.
TLDR
The incidence of sarcoidosis estimated in this study was similar to that of other Mediterranean countries, and male presented an incidence peak 10 years earlier than female. Expand
Pulmonary Sarcoidosis: Prognostic Factors at Diagnosis in Patients from North of Portugal
TLDR
Investigating prognostic factors at diagnosis in a population of sarcoidosis patients from Northern Portugal found clinical prognosis factors that have been described in other populations that should be considered whenever sarCOidosis is identified. Expand
Pulmonary Sarcoidosis: Prognostic Factors at Diagnosis in Patients from North of Portugal.
TLDR
In this first study searching for prognostic factors at diagnosis in a Northern Portuguese population, clinical prognosis factors that have been described in other populations that should be considered whenever sarcoidosis is identified are found. Expand
Clinical features and outcomes of asymptomatic pulmonary sarcoidosis. A comparative cohort study.
TLDR
APS showed earlier radiological stages, lesser impairment in lung function, extrapulmonary organ involvement and need for treatment than SnLS, and EBUS was the most useful diagnostic tool. Expand
Ocular sarcoidosis: clinical experience and recent pathogenetic and therapeutic advancements
TLDR
Uveitis of protean type, onset, duration, and course remains the most frequent ocular manifestation of SS and an ophthalmologist should be a constant component in the multidisciplinary approach to the treatment of this often challenging but intriguing disease. Expand
Clinical phenotypes and prediction of chronicity in sarcoidosis using cluster analysis in a prospective cohort of 694 patients.
TLDR
Cluster analysis identified 6 different clinical patterns with similar phenotypic variables and predicted chronicity in a large cohort of patients with sarcoidosis, which may help physicians to improve the efficacy of clinical decisions. Expand
...
1
2
3
4
5
...

References

SHOWING 1-10 OF 79 REFERENCES
Presenting characteristics as predictors of duration of treatment in sarcoidosis.
TLDR
Use of systemic therapy within the first 6 months after diagnosis appears to be strongly associated with continued use of therapy 2 years later, and the level of dyspnoea and therapy at initial visit remained significant. Expand
The clinical course of sarcoidosis: presentation, diagnosis, and treatment in a large white and black cohort in the United States.
TLDR
It is indicated that sarcoidosis tends to improve over time in terms of pulmonary function and medication requirements, and the disease was found to be more severe in blacks than whites. Expand
Sarcoidosis: epidemiology and prognosis. A 15-year European study.
TLDR
Patients with Stage I sarcoidosis, i.e., with bilateral hilar adenopathy alone, had the best prognosis, with 50% of the patients showing a normal radiographic picture 15 months after the discovery of the disease. Expand
Clinical factors predicting persistence of activity in sarcoidosis: a multivariate analysis of 193 cases.
TLDR
It is suggested that the identification of factors predicting persistence of sarcoidosis activity at diagnosis may help to establish the prognosis of the disease and therefore improve the therapeutic approach. Expand
Recurrent sarcoidosis: a study of 17 patients with 24 episodes of recurrence.
TLDR
Acute sarcoidosis, and particularly Löfgren's syndrome, may recur many years after complete remission and, in general, still has a good outcome, so a long-term follow-up is recommended even in patients with inactive disease. Expand
Sinonasal Involvement in Sarcoidosis: A Case-Control Study of 20 Patients
TLDR
Patients with SNS had significantly more frequent and severe involvement of vital organs than controls, had a longer history of sarcoidosis, and required systemic treatment more frequently and for a longer time. Expand
MANIFESTATIONS OF SARCOIDOSIS. ANALYSIS OF 145 PATIENTS, WITH A REVIEW OF NINE SERIES SELECTED FROM THE LITERATURE.
TLDR
No statistically significant difference in sarcoid manifestations was found primarily due to sex or race except for a higher incidence of hypoalbuminemia and hyperglobulinemia in Negro subjects. Expand
Cumulative Incidence and Predictors of Progression in Corticosteroid-Naïve Patients with Sarcoidosis
TLDR
In corticosteroid-naïve sarcoidosis patients, the risks of disease progression are comparable from 0–5 years and 5–10 years after diagnosis, and the number of organs involved at diagnosis is a useful predictor for progression of sarCOidosis. Expand
Clinical characteristics of patients in a case control study of sarcoidosis.
TLDR
It is concluded that the initial presentation of sarcoidosis is related to sex, race, and age. Expand
The clinical management of sarcoidosis. A 50-year experience at the Johns Hopkins Hospital.
TLDR
The management issues and guidelines outlined in this paper are based on several longitudinal studies of the sarcoidosis patients summarized here, and 50 years of clinical experience by the senior author at Johns Hopkins Hospital, a tertiary referral center with an active Sarcoid Clinic. Expand
...
1
2
3
4
5
...