Multidimension cultivation analysis by standard and omics methods for optimization of therapeutics production

Abstract

Background During the last decades Chinese Hamster Ovary (CHO) cells have been extensively used for research and biotechnological applications. About 40% of newly approved glycosylated protein pharmaceuticals are produced in CHO cells today [1]. Despite the increasing relevance of these cells for biopharmaceutical production little is known about effects of… (More)

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