Multidentate polyethylene glycol modified gold nanorods for in vivo near-infrared photothermal cancer therapy.

  title={Multidentate polyethylene glycol modified gold nanorods for in vivo near-infrared photothermal cancer therapy.},
  author={Xiangsheng Liu and Nan Huang and Huan Li and Hai-Bo Wang and Qiao Jin and Jian Ji},
  journal={ACS applied materials & interfaces},
  volume={6 8},
Gold nanorods (AuNRs), because of their strong absorption of near-infrared (NIR) light, are very suitable for in vivo photothermal therapy of cancer. However, appropriate surface modification must be performed on AuNRs before their in vivo application because of the high toxicity of their original stabilizer cetyltrimethylammonium bromide. Multidentate ligands have attracted a lot of attention for modification of inorganic nanoparticles (NPs) because of their high ligand affinity and… CONTINUE READING
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