Multicomponent strategy to indeno[2,1-c]pyridine and hydroisoquinoline derivatives through cleavage of carbon–carbon bond.

@article{Feng2015MulticomponentST,
  title={Multicomponent strategy to indeno[2,1-c]pyridine and hydroisoquinoline derivatives through cleavage of carbon–carbon bond.},
  author={Xian Feng and Jianjun Wang and Zhan Xun and Zhibin Huang and Da-Qing Shi},
  journal={The Journal of organic chemistry},
  year={2015},
  volume={80 2},
  pages={1025-33}
}
A concise and efficient three-component domino reaction has been developed for the synthesis of polyfunctionalized indenopyridine and hydroisoquinoline derivatives via the cleavage of a C–C bond under transition-metal-free conditions. This reaction provides facile access to complex nitrogen-containing heterocycles by simply mixing three common starting… CONTINUE READING