Multichannel intraluminal impedance and pH monitoring in gastroesophageal reflux disease.

@article{Vela2008MultichannelII,
  title={Multichannel intraluminal impedance and pH monitoring in gastroesophageal reflux disease.},
  author={Marcelo F. Vela},
  journal={Expert review of gastroenterology & hepatology},
  year={2008},
  volume={2 5},
  pages={665-72}
}
The role of acid is very well established in the pathogenesis of gastroesophageal reflux disease and acid suppression constitutes the main approach to its medical treatment. With the current frequent use of proton pump inhibitors, we are seeing increasing numbers of patients in whom symptoms persist despite pharmacological acid suppression. Reflux monitoring has been traditionally performed through esophageal pH measurement to detect acid reflux (i.e., drops in esophageal pH to below 4.0… CONTINUE READING