Multicentric reticulohistiocytosis: a proliferation of macrophages with tropism for skin and joints, part I.

Abstract

The authors present part I of a review of multicentric reticulohistiocytosis, a rare systemic proliferative disease of histiocytes of unknown cause. It is clinically characterized by cutaneous and mucosal nodules and by osteoarticular lesions. The disease occurs in outbreaks that progress in severity, with spontaneous regression, but usually leaving incapacitating arthritis and disfiguring facial lesions. The authors discuss the historical, epidemiologic, and clinical aspects of this disease.

Cite this paper

@article{Luz2007MulticentricRA, title={Multicentric reticulohistiocytosis: a proliferation of macrophages with tropism for skin and joints, part I.}, author={Fl{\'a}vio Barbosa Luz and Neide Kalil Gaspar and Antonio Pedro Gaspar and Sueli Coelho da Silva Carneiro and Marcia Ramos-E-Silva}, journal={Skinmed}, year={2007}, volume={6 4}, pages={172-8} }