Multicentric outcome analysis of sirolimus-based immunosuppression in 252 liver transplant recipients.

@article{Molinari2010MulticentricOA,
  title={Multicentric outcome analysis of sirolimus-based immunosuppression in 252 liver transplant recipients.},
  author={Michele Molinari and Kenneth H Berman and Glenda A. Meeberg and James Andrew Mark Shapiro and David L Bigam and James Ford Trotter and Norman Mark Kneteman},
  journal={Transplant international : official journal of the European Society for Organ Transplantation},
  year={2010},
  volume={23 2},
  pages={155-68}
}
SUMMARY The use of sirolimus (SRL) in orthotopic liver transplantation (OLT) has been controversial after experimental data suggested an increased risk of hepatic artery thrombosis (HAT). To assess the safety and efficacy of SRL as de novo immunosuppression in OLT recipients. Outcomes of 252 OLT patients who received SRL were compared with outcomes of 291 OLT recipients who received calcineurin inhibitor in a retrospective study. Primary outcomes of this study were: patient- and graft survivals… CONTINUE READING

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