Multicentre proton magnetic resonance spectroscopy imaging of primary progressive multiple sclerosis.

@article{Narayana2004MulticentrePM,
  title={Multicentre proton magnetic resonance spectroscopy imaging of primary progressive multiple sclerosis.},
  author={Ponnada A. Narayana and Jerry S. Wolinsky and S Bhanojee Rao and Renjie He and Meghana N Mehta},
  journal={Multiple sclerosis},
  year={2004},
  volume={10 Suppl 1},
  pages={
          S73-8
        }
}
Multicentre baseline proton magnetic resonance spectroscopic data on primary progressive multiple sclerosis (PPMS) patients are acquired and analysed, using automatic analysis software. The metabolite ratios did not differ from centre to centre. The average N-acetylaspartate/creatine (NAA/Cr) ratio in PPMS was significantly lower compared to normal controls. No significant differences were observed in this ratio between lesion-containing regions (LCR) and normal-appearing tissues (NAT). Strong… CONTINUE READING
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