Multicenter retrospective development and validation of a clinical prediction rule for nosocomial invasive candidiasis in the intensive care setting

@article{OstroskyZeichner2007MulticenterRD,
  title={Multicenter retrospective development and validation of a clinical prediction rule for nosocomial invasive candidiasis in the intensive care setting},
  author={L. Ostrosky-Zeichner and C. Sable and J. Sobel and B. Alexander and G. Donowitz and V. Kan and C. A. Kauffman and D. Kett and R. Larsen and V. Morrison and M. Nucci and P. Pappas and M. E. Bradley and S. Major and L. Zimmer and D. Wallace and W. Dismukes and J. Rex},
  journal={European Journal of Clinical Microbiology & Infectious Diseases},
  year={2007},
  volume={26},
  pages={271-276}
}
  • L. Ostrosky-Zeichner, C. Sable, +15 authors J. Rex
  • Published 2007
  • Medicine
  • European Journal of Clinical Microbiology & Infectious Diseases
  • The study presented here was performed in order to create a rule that identifies subjects at high risk for invasive candidiasis in the intensive care setting. Retrospective review and statistical modelling were carried out on 2,890 patients who stayed at least 4 days in nine hospitals in the USA and Brazil; the overall incidence of invasive candidiasis in this group was 3% (88 cases). The best performing rule was as follows: Any systemic antibiotic (days 1–3) OR presence of a central venous… CONTINUE READING
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