Multicenter randomized controlled trial for the treatment of ulcerative colitis with a leukocytapheresis column.

@article{Sawada2003MulticenterRC,
  title={Multicenter randomized controlled trial for the treatment of ulcerative colitis with a leukocytapheresis column.},
  author={Koji Sawada and Tetsuichiro Muto and Takashi Shimoyama and Masamichi Satomi and Toshio Sawada and Hirokazu Nagawa and Nobuo Hiwatashi and Hitoshi Asakura and Toshifumi Hibi},
  journal={Current pharmaceutical design},
  year={2003},
  volume={9 4},
  pages={
          307-21
        }
}
The administration of steroids is not always effective for the treatment of ulcerative colitis (UC). Their long-term use often causes adverse effects which sometimes result in their stoppage and acute exacerbation. Therefore, an alternative treatment is necessary in order to decrease steroid dosage and avoid the clinical problems associated with steroids. Methods The effectiveness and adverse effects of a leukocytapheresis (LCAP) were investigated in a controlled multicenter trial with… CONTINUE READING