Multicenter phase III trial studying trospium chloride in patients with overactive bladder.

  title={Multicenter phase III trial studying trospium chloride in patients with overactive bladder.},
  author={Delbert C Rudy and Kevin Cline and Richard P. Harris and Kenneth D Goldberg and Roger R Dmochowski},
  volume={67 2},
OBJECTIVES To study the efficacy and safety of trospium chloride in treating overactive bladder. Trospium chloride is an anticholinergic agent with predominantly peripheral nonselective antimuscarinic activity and thus has potential therapeutic value in treating patients with overactive bladder. METHODS Patients with overactive bladder were randomized on a 1:1 basis to either placebo or trospium chloride 20 mg twice daily in this 12-week, multicenter, parallel, double-blind, placebo… CONTINUE READING


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