Multicenter phase II trial of Genexol-PM, a Cremophor-free, polymeric micelle formulation of paclitaxel, in patients with metastatic breast cancer

@article{Lee2007MulticenterPI,
  title={Multicenter phase II trial of Genexol-PM, a Cremophor-free, polymeric micelle formulation of paclitaxel, in patients with metastatic breast cancer},
  author={Keun Seok Lee and Hyun Cheol Chung and Seock Ah Im and Yeon Hee Park and Chul Soo Kim and Sung- Bae Kim and Sun Young Rha and Min Young Lee and Jungsil Ro},
  journal={Breast Cancer Research and Treatment},
  year={2007},
  volume={108},
  pages={241-250}
}
Genexol-PM is a novel Cremophor EL-free polymeric micelle formulation of paclitaxel. This single arm, multicenter phase II study was designed to evaluate the efficacy and safety of Genexol-PM in patients with histologically confirmed metastatic breast cancer (MBC). Forty-one women received Genexol-PM by intravenous infusion at 300 mg/m2 over 3 h every 3 weeks without premedication until disease progression or intolerability. A total of 331 chemotherapy cycles were administered, with a median of… CONTINUE READING
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