Multicenter comparison of nucleic acid extraction methods for detection of severe acute respiratory syndrome coronavirus RNA in stool specimens.

@article{Petrich2006MulticenterCO,
  title={Multicenter comparison of nucleic acid extraction methods for detection of severe acute respiratory syndrome coronavirus RNA in stool specimens.},
  author={Astrid K Petrich and James Mahony and Sylvia Chong and George C Broukhanski and Farhad Gharabaghi and Grant Johnson and Lisa Louie and Kathy E Luinstra and Barbara M. Willey and P. Akhaven and Linda Chui and Frances B. Jamieson and Marie Louie and Tony Mazzulli and Raymond Tellier and Marek Smieja and Wenjie Cai and Max A Chernesky and Susan E Richardson},
  journal={Journal of clinical microbiology},
  year={2006},
  volume={44 8},
  pages={2681-8}
}
The emergence of a novel coronavirus (CoV) as the cause of severe acute respiratory syndrome (SARS) catalyzed the development of rapid diagnostic tests. Stool samples have been shown to be appropriate for diagnostic testing for SARS CoV, although it has been recognized to be a heterogeneous and difficult sample that contains amplification inhibitors. Limited information on the efficiency of extraction methods for the purification and concentration of SARS CoV RNA from stool samples is available… CONTINUE READING
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