Multicenter comparison of in vitro activities of FK-037, cefepime, ceftriaxone, ceftazidime, and cefuroxime.

@article{Washington1993MulticenterCO,
  title={Multicenter comparison of in vitro activities of FK-037, cefepime, ceftriaxone, ceftazidime, and cefuroxime.},
  author={John A. Washington and Ronald N. Jones and E. Hugh Gerlach and Patrick R. Murray and Stephen D Allen and Cindy C. Knapp},
  journal={Antimicrobial agents and chemotherapy},
  year={1993},
  volume={37 8},
  pages={1696-700}
}
In a multicenter study, the MICs of FK-037 for 90% of the strains tested (MIC90s) were < or = 1 microgram/ml for members of the family Enterobacteriaceae other than Citrobacter freundii, Enterobacter spp., and Serratia marcescens. Activity against Pseudomonas aeruginosa was variable, with a MIC50 and a MIC90 of 4 and 32 micrograms/ml, respectively. Relative to cefepime, however, FK-037 was less active against ceftazidime-resistant isolates of Enterobacter cloacae. The MIC90 of FK-037 for… CONTINUE READING