Multicenter Study of Method-Dependent Epidemiological Cutoff Values for Detection of Resistance in Candida spp. and Aspergillus spp. to Amphotericin B and Echinocandins for the Etest Agar Diffusion Method.

@article{EspinelIngroff2017MulticenterSO,
  title={Multicenter Study of Method-Dependent Epidemiological Cutoff Values for Detection of Resistance in Candida spp. and Aspergillus spp. to Amphotericin B and Echinocandins for the Etest Agar Diffusion Method.},
  author={Ana Victoria Espinel-Ingroff and M. Arendrup and Emilia Cant{\'o}n and Susana C{\'o}rdoba and Eric Dannaoui and Julio Garc{\'i}a-Rodr{\'i}guez and Gloria Mar{\'i}a Gonz{\'a}lez and Nelesh P Govender and estrella Martin-Mazuelos and Michaela Lackner and Cornelia Lass-Fl{\"o}rl and Mar{\'i}a Jos{\'e} Linares Sicilia and Manuel Antonio Rodr{\'i}guez-Iglesias and Teresa Pel{\'a}ez and Ryan K. Shields and Guillermo Garc{\'i}a-Effr{\'o}n and Jes{\'u}s Guinea and Maurizio Sanguinetti and John D. Turnidge},
  journal={Antimicrobial agents and chemotherapy},
  year={2017},
  volume={61 1}
}
Method-dependent Etest epidemiological cutoff values (ECVs) are not available for susceptibility testing of either Candida or Aspergillus species with amphotericin B or echinocandins. In addition, reference caspofungin MICs for Candida spp. are unreliable. Candida and Aspergillus species wild-type (WT) Etest MIC distributions (microorganisms in a species-drug combination with no detectable phenotypic resistance) were established for 4,341 Candida albicans, 113 C. dubliniensis, 1,683 C. glabrata… CONTINUE READING
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