Multicenter Comparison of Lung and Oral Microbiomes of HIV-infected and HIV-uninfected Individuals.

  title={Multicenter Comparison of Lung and Oral Microbiomes of HIV-infected and HIV-uninfected Individuals.},
  author={James M. Beck and Patrick D. Schloss and Arvind Venkataraman and Homer L Twigg and Kathleen A. Jablonski and Frederic D. Bushman and Thomas B. Campbell and Emily S. Charlson and Ronald G. Collman and Kristina Crothers and Jeffrey L Curtis and Kimberly L. Drews and S Cisneros Flores and Andrew P Fontenot and Mary A. Foulkes and Ian Frank and Elodie Ghedin and Laurence Huang and Susan V. Lynch and Alison M Morris and Brent E. Palmer and Thomas M Schmidt and Erica Sodergren and George Weinstock and Vincent B Young},
  journal={American journal of respiratory and critical care medicine},
  volume={192 11},
RATIONALE Improved understanding of the lung microbiome in HIV-infected individuals could lead to better strategies for diagnosis, therapy, and prophylaxis of HIV-associated pneumonias. Differences in the oral and lung microbiomes in HIV-infected and HIV-uninfected individuals are not well defined. Whether highly active antiretroviral therapy influences these microbiomes is unclear. OBJECTIVES We determined whether oral and lung microbiomes differed in clinically healthy groups of HIV… CONTINUE READING
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