Multicellular tumor spheroid formation in duplex microcapsules for analysis of chemosensitivity.

@article{Sakai2012MulticellularTS,
  title={Multicellular tumor spheroid formation in duplex microcapsules for analysis of chemosensitivity.},
  author={Shinji Sakai and Kazuya Inamoto and Yang Liu and Shinji Tanaka and Shigeki Arii and Masahito Taya},
  journal={Cancer science},
  year={2012},
  volume={103 3},
  pages={549-54}
}
Multicellular tumor spheroids (MTS) are gaining increased recognition as valuable tools and key elements in anticancer drug discovery and tumor therapy test programs. However, the lack of reproducible and uniform MTS sizes is a major problem for pharmaceutical assays. Here, we show the usefulness of duplex microcapsules with a Ca-alginate gel membrane as a… CONTINUE READING