MultiLoc2: integrating phylogeny and Gene Ontology terms improves subcellular protein localization prediction

@article{Blum2009MultiLoc2IP,
  title={MultiLoc2: integrating phylogeny and Gene Ontology terms improves subcellular protein localization prediction},
  author={Torsten Blum and Sebastian Briesemeister and Oliver Kohlbacher},
  journal={BMC Bioinformatics},
  year={2009},
  volume={10},
  pages={274 - 274}
}
Knowledge of subcellular localization of proteins is crucial to proteomics, drug target discovery and systems biology since localization and biological function are highly correlated. In recent years, numerous computational prediction methods have been developed. Nevertheless, there is still a need for prediction methods that show more robustness and higher accuracy. We extended our previous MultiLoc predictor by incorporating phylogenetic profiles and Gene Ontology terms. Two different… CONTINUE READING
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