Multi-walled carbon nanotubes induce cytotoxicity and genotoxicity in human lung epithelial cells.

  title={Multi-walled carbon nanotubes induce cytotoxicity and genotoxicity in human lung epithelial cells.},
  author={Delia Cavallo and C. Fanizza and Cinzia Lucia Ursini and Stefano Casciardi and Emilia Paba and Aureliano Ciervo and Anna Maria Fresegna and Raffaele Maiello and Anna Maria Marcelloni and Giuliana Buresti and Francesca Tombolini and Stefano Bellucci and Sergio Iavicoli},
  journal={Journal of applied toxicology : JAT},
  volume={32 6},
The increasing use of nanomaterials in consumer products highlights the importance of understanding their potential toxic effects. We evaluated cytotoxic and genotoxic/oxidative effects induced by commercial multi-walled carbon nanotubes (MWCNTs) on human lung epithelial (A549) cells treated with 5, 10, 40 and 100 µg ml⁻¹ for different exposure times. Scanning electron microscopy (SEM) analysis, MTT [3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide] and lactate dehydrogenase (LDH… CONTINUE READING


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