Multi-walled carbon nanotubes induce apoptosis via mitochondrial pathway and scavenger receptor.

@article{Wang2012MultiwalledCN,
  title={Multi-walled carbon nanotubes induce apoptosis via mitochondrial pathway and scavenger receptor.},
  author={Xiang Wang and Jian Guo and Tian Ze Chen and Haiyu Nie and Haifang Wang and Jiajie Zang and Xiaoxing Cui and Guang Jia},
  journal={Toxicology in vitro : an international journal published in association with BIBRA},
  year={2012},
  volume={26 6},
  pages={799-806}
}
We have demonstrated previously that the acid-treated multi-walled carbon nanotubes (aci-MWCNTs) and taurine functionalized MWCNTs (tau-MWCNTs) induced differential pulmonary toxicity in mice after instillation exposure. In order to compare differences of cytotoxicity between the aci- and tau-MWCNTs, RAW 264.7 cells (a murine macrophage cell line) were chosen to be exposed to the aci- and tau-MWCNTs at concentrations of 0, 5, 20, 40, and 80μg/ml for 12 or 24h respectively. The results showed… CONTINUE READING