Multi-walled carbon nanotube-induced gene expression in the mouse lung: association with lung pathology.

@article{Pacurari2011MultiwalledCN,
  title={Multi-walled carbon nanotube-induced gene expression in the mouse lung: association with lung pathology.},
  author={Maricica Pacurari and Yong Qian and Dale W. Porter and Michael W. Wolfarth and Ying-Wooi Wan and Dajie Luo and M. Ding and Vincent Castranova and Nancy Lan Guo},
  journal={Toxicology and applied pharmacology},
  year={2011},
  volume={255 1},
  pages={
          18-31
        }
}
Due to the fibrous shape and durability of multi-walled carbon nanotubes (MWCNT), concerns regarding their potential for producing environmental and human health risks, including carcinogenesis, have been raised. This study sought to investigate how previously identified lung cancer prognostic biomarkers and the related cancer signaling pathways are affected in the mouse lung following pharyngeal aspiration of well-dispersed MWCNT. A total of 63 identified lung cancer prognostic biomarker genes… CONTINUE READING

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Multiwalled carbon nanotube-induced gene signatures in the mouse lung: potential predictive value for human lung cancer risk and prognosis.

  • Journal of toxicology and environmental health. Part A
  • 2012
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