Multi-trait analysis for genome-wide association study of five psychiatric disorders

@article{Wu2020MultitraitAF,
  title={Multi-trait analysis for genome-wide association study of five psychiatric disorders},
  author={Yulu Wu and Hongbao Cao and Ancha V. Baranova and Hailiang Huang and Sheng Li and Lei Cai and Shuquan Rao and Minhan Dai and Min Xie and Yikai Dou and Qinjian Hao and Ling Zhu and Xiangrong Zhang and Yin Yao and Fuquan Zhang and Mingqing Xu and Qiang Wang},
  journal={Translational Psychiatry},
  year={2020},
  volume={10}
}
We conducted a cross-trait meta-analysis of genome-wide association study on schizophrenia (SCZ) ( n  = 65,967), bipolar disorder (BD) ( n  = 41,653), autism spectrum disorder (ASD) ( n  = 46,350), attention deficit hyperactivity disorder (ADHD) ( n  = 55,374), and depression (DEP) ( n  = 688,809). After the meta-analysis, the number of genomic loci increased from 14 to 19 in ADHD, from 3 to 10 in ASD, from 45 to 57 in DEP, from 8 to 54 in BD, and from 64 to 87 in SCZ. We observed significant… 
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