Multi-tasking of helper T cells.

  title={Multi-tasking of helper T cells.},
  author={Yisong Y. Wan},
  volume={130 2},
CD4 T helper cells (Th) are critical in combating pathogens and maintaining immune homeostasis. Since the establishment of the Th1-Th2 paradigm in the 1980s, many types of specialized Th cells, including Th1, Th2, Th17, Th9, follicular helper T and regulatory T, have been identified. We have become accustomed to the idea that different Th cells are 'committed' to their paths but recent emerging evidence suggests that under certain conditions, seemingly committed Th cells possess plasticity and… CONTINUE READING

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