Multi-targeting therapeutic mechanisms of the Chinese herbal medicine QHD in the treatment of non-alcoholic fatty liver disease

@inproceedings{Feng2017MultitargetingTM,
  title={Multi-targeting therapeutic mechanisms of the Chinese herbal medicine QHD in the treatment of non-alcoholic fatty liver disease},
  author={Qin Feng and Wen-sheng Liu and Susan Sestini Baker and Hongshan Li and Cheng Chen and Qian Liu and Shijie Tang and Lingyu Guan and Maria Tsompana and Rafal Kozielski and Robert Dawson Baker and Jing-hua Peng and Ping Liu and Ruixin Zhu and Yiyang Hu and Lixin Zhu},
  booktitle={Oncotarget},
  year={2017}
}
Beneficial effects of the Chinese herbal medicine Qushi Huayu Decoction (QHD) were observed with non-alcoholic fatty liver disease (NAFLD) patients and animal models. The impact of QHD or its active components (geniposide and chlorogenic acid, GC) on NAFLD liver transcriptome and gut microbiota was examined with NAFLD rats. Increased expression for genes required for glutathione production and decreased expression for genes required for lipid synthesis was observed in NAFLD livers treated with… CONTINUE READING

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