Multi-stimuli responsive Cu2S nanocrystals as trimodal imaging and synergistic chemo-photothermal therapy agents.
@article{Poulose2015MultistimuliRC, title={Multi-stimuli responsive Cu2S nanocrystals as trimodal imaging and synergistic chemo-photothermal therapy agents.}, author={A. C. Poulose and S. Veeranarayanan and M. S. Mohamed and Y. Nagaoka and R. R. Aburto and T. Mitcham and P. Ajayan and R. Bouchard and Y. Sakamoto and Yasuhiko Yoshida and T. Maekawa and D. S. Kumar}, journal={Nanoscale}, year={2015}, volume={7 18}, pages={ 8378-8388 } }
A size and shape tuned, multifunctional metal chalcogenide, Cu2S-based nanotheranostic agent is developed for trimodal imaging and multimodal therapeutics against brain cancer cells. This theranostic agent was highly efficient in optical, photoacoustic and X-ray contrast imaging systems. The folate targeted NIR-responsive photothermal ablation in synergism with the chemotherapeutic action of doxorubicin proved to be a rapid precision guided cancer-killing module. The multi-stimuli, i.e., pH… CONTINUE READING
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