Multi-scale non-local means with shape prior for enhancement of cell membrane images

  title={Multi-scale non-local means with shape prior for enhancement of cell membrane images},
  author={Cheng-Jin Du and R. Tyson and E. Rozbicki and Cornells J. Weijer and Till Bretschneider},
  journal={2014 IEEE 11th International Symposium on Biomedical Imaging (ISBI)},
  • Cheng-Jin Du, R. Tyson, +2 authors Till Bretschneider
  • Published 2014
  • Mathematics, Computer Science
  • 2014 IEEE 11th International Symposium on Biomedical Imaging (ISBI)
  • Light sheet microscopy allows rapid optical sectioning of whole chicken embryos during early development, visualizing cells through transgenic expression of a fluorescent cell membrane label. Low signal-to-noise ratios and large variability in intensity make segmentation of these images difficult, often resulting in discontinuous cell edges. We propose a multi-scale non-local means with shape prior (MS-NLM-SP) method for image enhancement, which takes into account cell-specific characteristics… CONTINUE READING


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