Multi-level regulation of cellular recognition of viral dsRNA

Abstract

Effective antiviral immunity depends on accurate recognition of viral RNAs by the innate immune system. Double-stranded RNA (dsRNA) often accumulates in virally infected cells and was initially considered a unique viral signature that was sufficient to initiate antiviral response through dsRNA receptors and dsRNA-dependent effectors such as Toll-like… (More)
DOI: 10.1007/s00018-012-1149-4

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