Multi-ion conduction and selectivity in the high-conductance Ca++-activated K+ channel from skeletal muscle.

@article{Eisenman1986MultiionCA,
  title={Multi-ion conduction and selectivity in the high-conductance Ca++-activated K+ channel from skeletal muscle.},
  author={George Eisenman and Ram{\'o}n Latorre and Chad G. Miller},
  journal={Biophysical journal},
  year={1986},
  volume={50 6},
  pages={1025-34}
}
Open-channel ion permeation properties were investigated for Ca++-activated K+ (CaK) channels in solutions of K+ and its analogues T1+, Rb+, and NH4+. Single CaK channels were inserted into planar lipid bilayers composed of neutral phospholipids, and open-channel current-voltage (I-V) relations were measured in symmetrical and asymmetrical solutions of each of these individual ions. For all concentrations studied, the zero-voltage conductance falls in the sequence K+ greater than T1+ greater… CONTINUE READING
61 Citations
0 References
Similar Papers

Citations

Publications citing this paper.
Showing 1-10 of 61 extracted citations

Similar Papers

Loading similar papers…