Multi-institutional Study of Outcomes After Pediatric Heart Transplantation: Candidate Gene Polymorphism Analysis of ABCC2.

@article{Burckart2014MultiinstitutionalSO,
  title={Multi-institutional Study of Outcomes After Pediatric Heart Transplantation: Candidate Gene Polymorphism Analysis of ABCC2.},
  author={Gilbert J. Burckart and William D. Figg and Maria Mori Brooks and Dionna J Green and Sarah M. Troutman and Robert E. Ferrell and Richard E Chinnock and Charles E. Canter and Linda J. Addonizio and Daniel Bernstein and James K. Kirklin and David C. Naftel and Douglas K. Price and Tristan Sissung and Diana M Girnita and Adriana Zeevi and S. A. Webber},
  journal={The journal of pediatric pharmacology and therapeutics : JPPT : the official journal of PPAG},
  year={2014},
  volume={19 1},
  pages={16-24}
}
OBJECTIVES Earlier studies have indicated that the pharmacokinetics of mycophenolic acid (MPA) is influenced by polymorphisms of ABCC2, which encodes for the membrane transporter MRP2. The ABCC2 rs717620 A allele has been associated with enterohepatic recirculation of MPA, and our previous work had correlated the discontinuance of MPA with this allele in… CONTINUE READING