Multi-germ layer lineage central nervous system repair: nerve and vascular cell generation by embryonic stem cells transplanted in the injured brain.

Abstract

OBJECT To restore proper function to a damaged central nervous system (CNS) through transplantation, it is necessary to replace both neural and nonneural elements that arise from different germ layers in the embryo. Mounting evidence indicates the importance of signals related to vasculogenesis in governing neural proliferation and differentiation in early… (More)

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Cite this paper

@article{Vadivelu2005MultigermLL, title={Multi-germ layer lineage central nervous system repair: nerve and vascular cell generation by embryonic stem cells transplanted in the injured brain.}, author={Sudhakar Vadivelu and Marina M Platik and Luke Choi and Molly L Lacy and Aarti R. Shah and Yun Yan Qu and Terrence F. Holekamp and Daniel M. Becker and David I. Gottlieb and Jeffrey M. Gidday and John W. McDonald}, journal={Journal of neurosurgery}, year={2005}, volume={103 1}, pages={124-35} }