Multi-faced neuroprotective effects of geniposide depending on the RAGE-mediated signaling in an Alzheimer mouse model.

Abstract

The receptor for advanced glycation end products (RAGE)-mediated signaling pathway is related to Aβ-induced pathogenic responses. Geniposide, a pharmacologically active component purified from gardenia fruit, could attenuate the oligomeric Aβ(1-42)-induced inflammatory response by blocking the ligation of Aβ to RAGE and suppressing the RAGE-mediated… (More)
DOI: 10.1016/j.neuropharm.2014.09.019

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@article{Lv2015MultifacedNE, title={Multi-faced neuroprotective effects of geniposide depending on the RAGE-mediated signaling in an Alzheimer mouse model.}, author={Cui Lv and Lei Wang and Xiaoli Liu and Shijun Yan and Shirley ShiDu Yan and Yongyan Wang and Wensheng Zhang}, journal={Neuropharmacology}, year={2015}, volume={89}, pages={175-84} }