Multi-dynein hypothesis.

  title={Multi-dynein hypothesis.},
  author={David J. Asai},
  journal={Cell motility and the cytoskeleton},
  volume={32 2},
  • David J. Asai
  • Published 1995 in Cell motility and the cytoskeleton
Axonemal dyneins and cytoplasmic dynein have evolved separate strategies to perform their tasks. The multi-dynein hypothesis accurately describes the highly specialized axonemal isoforms; each isoform is encoded by a separate gene, is located in a precise place, produces specific forces which contribute to the overall generation of propagated bending, and is not functionally interchangeable with other isoforms. In contrast, cytoplasmic dynein, although carrying many different cargoes, appears… CONTINUE READING