Multi-drug loaded polymeric micelles for simultaneous delivery of poorly soluble anticancer drugs.

Abstract

Current clinical and preclinical anticancer formulations are limited by their use of toxic excipients and stability issues upon combining different drug formulations. We have found that poly(ethylene glycol)-block-poly(d,l lactic acid) (PEG-b-PLA) micelles can deliver multiple poorly water-soluble drugs at clinically relevant doses. Paclitaxel (PTX… (More)
DOI: 10.1016/j.jconrel.2009.04.024

Topics

8 Figures and Tables

Slides referencing similar topics