Multi-centre reproducibility of diffusion MRI parameters for clinical sequences in the brain

  title={Multi-centre reproducibility of diffusion MRI parameters for clinical sequences in the brain},
  author={Matthew Grech-Sollars and Patrick W. Hales and Keiko Miyazaki and Felix Raschke and Daniel Rodriguez and Martin Wilson and Simrandip K. Gill and Tina Banks and Dawn Saunders and Jonathan D. Clayden and Matt N Gwilliam and Thomas R. Barrick and Paul Simon Morgan and Nigel Paul Davies and James Rossiter and D P Auer and Richard G. Grundy and Martin O. Leach and Franklyn A. Howe and Andrew C Peet and Chris A Clark},
  booktitle={NMR in biomedicine},
The purpose of this work was to assess the reproducibility of diffusion imaging, and in particular the apparent diffusion coefficient (ADC), intra-voxel incoherent motion (IVIM) parameters and diffusion tensor imaging (DTI) parameters, across multiple centres using clinically available protocols with limited harmonization between sequences. An ice-water phantom and nine healthy volunteers were scanned across fives centres on eight scanners (four Siemens 1.5T, four Philips 3T). The mean ADC… CONTINUE READING


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