Multi-center determination of galectin-3 assay performance characteristics: Anatomy of a novel assay for use in heart failure.

@article{Christenson2010MulticenterDO,
  title={Multi-center determination of galectin-3 assay performance characteristics: Anatomy of a novel assay for use in heart failure.},
  author={Robert H. Christenson and Show-Hong Duh and Alan H. B. Wu and Andrew Charles Smith and Gyorgy Abel and Christopher deFilippi and Shunguang Wang and Aram S Adourian and Carol A Adiletto and Peter Gardiner},
  journal={Clinical biochemistry},
  year={2010},
  volume={43 7-8},
  pages={
          683-90
        }
}
BACKGROUND Galectin-3 is a carbohydrate binding protein that plays many important regulatory roles in inflammation, immunity and cancer. Recent studies indicate that galectin-3 is a mediator of heart failure development and progression. Development of an improved assay for galectin-3 measurement was necessary for appropriate clinical assessment. Key analytical performance characteristics, the reference distribution and association of galectin-3 levels with clinical outcome in heart failure… CONTINUE READING

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