Multi-Level Integration of Environmentally Perturbed Internal Phenotypes Reveals Key Points of Connectivity between Them

@inproceedings{Benis2017MultiLevelIO,
  title={Multi-Level Integration of Environmentally Perturbed Internal Phenotypes Reveals Key Points of Connectivity between Them},
  author={Nirupama Benis and Soumya Kar and V{\'i}tor A. P. Martins dos Santos and Mari A. Smits and Dirkjan Schokker and Mar{\'i}a Su{\'a}rez-Diez},
  booktitle={Front. Physiol.},
  year={2017}
}
The genotype and external phenotype of organisms are linked by so-called internal phenotypes which are influenced by environmental conditions. In this study, we used five existing -omics datasets representing five different layers of internal phenotypes, which were simultaneously measured in dietarily perturbed mice. We performed 10 pair-wise correlation analyses verified with a null model built from randomized data. Subsequently, the inferred networks were merged and literature mined for co… CONTINUE READING
Recent Discussions
This paper has been referenced on Twitter 15 times over the past 90 days. VIEW TWEETS

From This Paper

Figures, tables, and topics from this paper.
0 Citations
52 References
Similar Papers

References

Publications referenced by this paper.
Showing 1-10 of 52 references

The origin of correlations in

  • D. Camacho, A. De La Fuente, P. Mendes
  • METABOLOMICS
  • 2005
Highly Influential
1 Excerpt

Similar Papers

Loading similar papers…