Mulberry extract inhibits oleic acid-induced lipid accumulation via reduction of lipogenesis and promotion of hepatic lipid clearance.

@article{Ou2011MulberryEI,
  title={Mulberry extract inhibits oleic acid-induced lipid accumulation via reduction of lipogenesis and promotion of hepatic lipid clearance.},
  author={Ting-Tsz Ou and Man-Jung Hsu and Kuei-Chuan Chan and Chien-Ning Huang and Hsieh-Hsun Ho and Chau-Jong Wang},
  journal={Journal of the science of food and agriculture},
  year={2011},
  volume={91 15},
  pages={2740-8}
}
BACKGROUND Mulberries are a traditional edible food used to treat hepatic disease. The anti-obesity and hypolipidemic effects of mulberry water extracts (MWE) have attracted increasing interest. In the present study, MWE were assessed for their hepatic lipid-lowering potential when administered in fatty acid overload conditions in HepG2 cells. RESULTS We found that MWE significantly reduced lipid accumulation, suppressed fatty acid synthesis, and stimulated fatty acid oxidation. Furthermore… CONTINUE READING