Mucus proteinase inhibitor: a fast-acting inhibitor of leucocyte elastase.

@article{Boudier1989MucusPI,
  title={Mucus proteinase inhibitor: a fast-acting inhibitor of leucocyte elastase.},
  author={Christian Boudier and Joseph G. Bieth},
  journal={Biochimica et biophysica acta},
  year={1989},
  volume={995 1},
  pages={36-41}
}
Human mucus proteinase inhibitor is a fast-acting inhibitor of human leucocyte elastase (EC 3.4.21.37) and forms a stable, complex with this enzyme. At physiological ionic strength and temperature and in the presence of 10 mg/ml albumin, the kinetic constants characterizing the interaction between elastase and the non-degraded inhibitor are: kass = 6.4.10(6) M-1.s-1, kdiss = 2.3.10(-3) s-1, Ki = 3.10(-10) M. The partially degraded inhibitor isolated by chymotrypsin-Sepharose chromatography… CONTINUE READING