Mucus and alkali secretion in the rat duodenum: effects of indomethacin, N omega-nitro-L-arginine, and luminal acid.

@article{Sabab1995MucusAA,
  title={Mucus and alkali secretion in the rat duodenum: effects of indomethacin, N omega-nitro-L-arginine, and luminal acid.},
  author={M Sabab{\'i} and Eva Falk Nilsson and Lena Holm},
  journal={Gastroenterology},
  year={1995},
  volume={109 5},
  pages={1526-34}
}
BACKGROUND & AIMS Duodenal mucus and bicarbonate secretion appear to play an essential role in the protection of the duodenum. The aim of this study was to examine duodenal bicarbonate and mucus secretion and the effects of cyclooxygenase inhibition, nitric oxide synthase inhibition, and luminal acid. METHODS Duodenal mucus gel thickness was measured using microelectrodes during intravital microscopy in anesthetized rats. Bicarbonate secretion was measured using back-titration. RESULTS A… CONTINUE READING
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